Anti-PSCA Antibody from MyBioSource.com

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Anti-PSCA Antibody

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MyBioSource.com's Anti-PSCA Antibody is a Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-PSCA Antibody was generated using Prostate Stem Cell Antigen, and PSCA as the antigen and it reacts with Mouse, and Rat.

Description

Description: Rabbit IgG polyclonal antibody for Prostate stem cell antigen(PSCA) detection. Tested with WB in Human;Mouse;Rat.

Background: PSCA is also known as PRO232. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants